Primary Biosecurity Journals
- Health Security - Dedicated biosecurity and health security journal
- Biosecurity and Bioterrorism - Historical biosecurity literature
A curated collection of resources for further exploration of biosecurity topics covered in this handbook.
Koblentz, G. D. (2009). Living Weapons: Biological Warfare and International Security. Cornell University Press. - Comprehensive analysis of biological weapons as a security threat.
Guillemin, J. (2005). Biological Weapons: From the Invention of State-Sponsored Programs to Contemporary Bioterrorism. Columbia University Press. - Historical overview of state bioweapons programs.
Alibek, K. & Handelman, S. (1999). Biohazard: The Chilling True Story of the Largest Covert Biological Weapons Program in the World. Random House. - First-hand account of the Soviet Biopreparat program.
Tucker, J. B. (2012). Innovation, Dual Use, and Security: Managing the Risks of Emerging Biological and Chemical Technologies. MIT Press. - Analysis of dual-use challenges in emerging technologies.
Russell, S. (2019). Human Compatible: Artificial Intelligence and the Problem of Control. Viking. - Foundational text on AI safety.
Amodei, D. et al. Various Anthropic research papers on AI safety and responsible scaling.
Osterholm, M. T. & Olshaker, M. (2017). Deadliest Enemy: Our War Against Killer Germs. Little, Brown and Company. - Expert perspective on pandemic threats.
Quammen, D. (2012). Spillover: Animal Infections and the Next Human Pandemic. W. W. Norton. - Accessible exploration of zoonotic disease emergence.
CDC Bioterrorism Agents/Diseases - Official CDC categorization of biological threat agents.
CDC BMBL (Biosafety in Microbiological and Biomedical Laboratories) - The definitive U.S. biosafety reference.
OSTP AI Biodefense Framework (2024) - U.S. policy framework for AI and biosecurity.
P3CO Policy - Potential Pandemic Pathogen Care and Oversight framework.
WHO Laboratory Biosafety Manual (4th Edition) - Global biosafety guidance.
BWC Implementation Support Unit - Treaty texts and implementation resources.
International Health Regulations (2005) - Legal framework for global health security.
RAND: The Operational Risks of AI in Large-Scale Biological Attacks (2024) - Comprehensive AI-bio risk assessment.
RAND: Protecting Biological Materials from Misuse (2025) - Supply chain chokepoints and access monitoring.
RAND: Mitigating AI-CBW Risks (2025) - DHS-commissioned assessment of AI and biological/chemical weapons.
RAND: Theoretical Limits of AI-Enabled Pathogen Design (2025) - Expert Delphi study on AI barriers and capabilities.
RAND: Securing Commercial Nucleic Acid Synthesis (2024) - Comprehensive screening policy recommendations.
RAND: Global Risk Index for AI-enabled Biological Tools (2025) - Risk assessment framework for AI-bio tools.
NTI Global Health Security Index - Country-level pandemic preparedness benchmarking.
Johns Hopkins CHS: Centerpiece Reports - Various biosecurity policy analyses.
| Organization | Focus | Website |
|---|---|---|
| CDC | Disease surveillance, biosafety | cdc.gov |
| BARDA | Medical countermeasure development | medicalcountermeasures.gov |
| IARPA | Advanced research including biosurveillance | iarpa.gov |
| USAMRIID | Military biodefense research | usamriid.health.mil |
| Select Agent Program | Pathogen regulation | selectagents.gov |
| Organization | Focus | Website |
|---|---|---|
| WHO | Global health security | who.int |
| FAO | Animal and plant health | fao.org |
| WOAH (OIE) | Animal health standards | woah.org |
| OPCW | Chemical weapons (overlap) | opcw.org |
| Organization | Focus | Website |
|---|---|---|
| NTI | Nuclear and biological threat reduction | nti.org |
| Johns Hopkins CHS | Health security policy | centerforhealthsecurity.org |
| RAND | Policy research | rand.org |
| RAND Meselson Center | Biosecurity research | rand.org/meselson |
| CSIS | Security studies | csis.org |
| CEPI | Epidemic preparedness | cepi.net |
| Organization | Focus | Website |
|---|---|---|
| Anthropic | Frontier Red Team, biosecurity evaluations | anthropic.com |
| OpenAI | Preparedness Framework | openai.com |
| Google DeepMind | AI safety research | deepmind.google |
| Fellowship | Organization | Focus |
|---|---|---|
| ELBI | Johns Hopkins CHS | Mid-career biosecurity leaders |
| Emerging Leaders Program | NTI | Nuclear and biological security |
| Biosecurity Initiative | Open Philanthropy | Research and career development |
| Platform | Purpose | Website |
|---|---|---|
| GISAID | Pathogen genomic data sharing | gisaid.org |
| ProMED | Outbreak reporting | promedmail.org |
| NCBI GenBank | Genetic sequence database | ncbi.nlm.nih.gov |
| Nextstrain | Pathogen evolution tracking | nextstrain.org |
| Our World in Data | Pandemic data visualization | ourworldindata.org |
What resources are recommended for learning biosecurity?
Start with foundational texts like Koblentz’s Living Weapons and the CDC BMBL (Biosafety in Microbiological and Biomedical Laboratories). Follow key organizations including CDC, BARDA, WHO, Johns Hopkins Center for Health Security, and NTI. Subscribe to ProMED for outbreak alerts and explore GISAID and Nextstrain for genomic surveillance. For AI-biosecurity convergence, review RAND’s recent reports and follow Anthropic and OpenAI’s biosecurity evaluations.
Where can I find biosecurity training programs?
Graduate programs include Johns Hopkins Bloomberg School of Public Health (health security concentration), Georgetown University’s Global Health Security and Security Master’s Program, MIT’s synthetic biology programs, and Stanford CISAC. Mid-career professionals can apply for the Emerging Leaders in Biosecurity Initiative (ELBI) at Johns Hopkins CHS, NTI’s Emerging Leaders Program, or Open Philanthropy’s Biosecurity Initiative fellowships.
How do I stay current on biosecurity policy and research?
Subscribe to ProMED for outbreak reports, CIDRAP for infectious disease news, and Stat News for health policy journalism. Follow journals including Health Security, The Lancet, Nature, and Science. Review policy reports from RAND (especially the Meselson Center), Johns Hopkins Center for Health Security, and NTI. Monitor OSTP and BARDA for U.S. policy updates, and track WHO and BWC Implementation Support Unit for international developments.
This appendix is part of The Biosecurity Handbook. Last updated: December 2025.